ISG15-dependent activation of the sensor MDA5 is antagonized by the SARS-CoV-2 papain-like protease to evade host innate immunity

Guanqun Liu, Jung‐Hyun Lee, Zachary M. Parker, +8

Nature Microbiology

Host ResponseHost Innate ImmunityImmunologyImmunologic MechanismIsg15-dependent Activation +5

Viral unmasking of cellular 5S rRNA pseudogene transcripts induces RIG-I-mediated immunity

Jessica J. Chiang, Konstantin M. J. Sparrer, Michiel van Gent, +5

Nature Immunology

Viral ReplicationViral UnmaskingCellular 5SImmunologyRrna Pseudogene Transcripts +7

Topology and Membrane Anchoring of the Coronavirus Replication Complex: Not All Hydrophobic Domains of nsp3 and nsp6 Are Membrane Spanning

Monique Oostra, Marne C. Hagemeijer, Michiel van Gent, +4

Journal of Virology

Virus StructureCoronavirus Replication ComplexLarge Replicase PolyproteinsViral ReplicationMembrane Anchoring +11

Epstein-Barr Virus Large Tegument Protein BPLF1 Contributes to Innate Immune Evasion through Interference with Toll-Like Receptor Signaling

Michiel van Gent, Steven Braem, Annemieke de Jong, +9

PLoS Pathogens

Innate Immune SystemImmunologyViral PathogenesisToll-like ReceptorInnate Immunity +15

EBV MicroRNA BART16 Suppresses Type I IFN Signaling

Marjolein J. G. Hooykaas, Michiel van Gent, Jasper A. Soppe, +8

The Journal of Immunology

EBV Lytic-Phase Protein BGLF5 Contributes to TLR9 Downregulation during Productive Infection

Michiel van Gent, Bryan D. Griffin, E. G. M. Berkhoff, +7

The Journal of Immunology

Human CD45 is an F-component-specific receptor for the staphylococcal toxin Panton–Valentine leukocidin

Angelino T. Tromp, Michiel van Gent, Pauline Abrial, +18

Nature Microbiology

AllergyMicrobial PathogensPathogenesisImmunologyImmunologic Mechanism +4

A transgenic zebrafish line for in vivo visualisation of neutrophil myeloperoxidase

Kyle D. Buchan, Tomasz K. Prajsnar, Nikolay V. Ogryzko, +6

PLoS ONE

High-throughput RNA sequencing of paraformaldehyde-fixed single cells

Hoang Van Phan, Michiel van Gent, Nir Drayman, +3

Nature Communications

Centrosomal protein TRIM43 restricts herpesvirus infection by regulating nuclear lamina integrity

Florian Full, Michiel van Gent, Konstantin M. J. Sparrer, +10

Nature Microbiology

ChromatinNuclear Lamina IntegrityViral ReplicationMolecular VirologyCentrosomal Protein Trim43 +7