Sacha Spelier

Oral Mucosal Organoids as a Potential Platform for Personalized Cancer Therapy

Else Driehuis, Sigrid Kolders, Sacha Spelier et al. · Cancer Discovery · 2019 · 399 citations · Full text

Patient-Derived Head and Neck Cancer Organoids Recapitulate EGFR Expression Levels of Respective Tissues and Are Responsive to EGFR-Targeted Photodynamic Therapy

Else Driehuis, Sacha Spelier, Irati Beltrán Hernández et al. · Journal of Clinical Medicine · 2019 · 98 citations · Full text

Measuring cystic fibrosis drug responses in organoids derived from 2D differentiated nasal epithelia

Gimano D. Amatngalim, Lisa W. Rodenburg, Bente L. Aalbers et al. · Life Science Alliance · 2022 · 45 citations · Full text

Functional Restoration of CFTR Nonsense Mutations in Intestinal Organoids

Eyleen de Poel, Sacha Spelier, S.W.F. Suen et al. · Journal of Cystic Fibrosis · 2021 · 38 citations · Full text

FDA-approved drug screening in patient-derived organoids demonstrates potential of drug repurposing for rare cystic fibrosis genotypes

Eyleen de Poel, Sacha Spelier, Marne C. Hagemeijer et al. · Journal of Cystic Fibrosis · 2023 · 37 citations · Full text

Fibrosis, Fda-approved Drug Screening, Pharmacology +5