Bente L. Aalbers

CRISPR-Based Adenine Editors Correct Nonsense Mutations in a Cystic Fibrosis Organoid Biobank

Maarten H. Geurts, Eyleen de Poel, Gimano D. Amatngalim et al. · Cell stem cell · 2020 · 220 citations · Full text

Life Sciences, Genetics, Molecular Genetics +12

Measuring cystic fibrosis drug responses in organoids derived from 2D differentiated nasal epithelia

Gimano D. Amatngalim, Lisa W. Rodenburg, Bente L. Aalbers et al. · Life Science Alliance · 2022 · 51 citations · Full text

Medicine, Cell Biology, Pharmacology +15

Forskolin induced swelling (FIS) assay in intestinal organoids to guide eligibility for compassionate use treatment in a CF patient with a rare genotype

Bente L. Aalbers, Jesse E. Brunsveld, Cornelis K. van der Ent et al. · Journal of Cystic Fibrosis · 2022 · 27 citations · Full text

Medicine, Molecular Medicine, Pathology +15

Clinical effect of lumacaftor/ivacaftor in F508del homozygous CF patients with FEV1 ≥ 90% predicted at baseline

Bente L. Aalbers, Karin M. de Winter‐de Groot, Hubertus G.M. Arets et al. · Journal of Cystic Fibrosis · 2020 · 26 citations · Full text

Medicine, Clinical Sciences, Molecular Genetics +9

Females with cystic fibrosis have a larger decrease in sweat chloride in response to lumacaftor/ivacaftor compared to males

Bente L. Aalbers, Regina W. Hofland, Inez Bronsveld et al. · Journal of Cystic Fibrosis · 2020 · 25 citations · Full text

Medicine, Pediatrics, Physiology +12