Hettie M. Janssens

A functional CFTR assay using primary cystic fibrosis intestinal organoids

Johanna F. Dekkers, Caroline L. Wiegerinck, Hugo R. de Jonge et al. · Nature Medicine · 2013 · 997 citations

Medicine, Cell Biology, Pharmacology +8

What the pulmonary specialist should know about the new inhalation therapies

Beth L. Laube, Hettie M. Janssens, Frans H. de Jongh et al. · European Respiratory Journal · 2011 · 802 citations · Full text

Pharmacy, Pediatrics, Respiratory Therapy +17

Characterizing responses to CFTR-modulating drugs using rectal organoids derived from subjects with cystic fibrosis

Johanna F. Dekkers, Gitte Berkers, Evelien Kruisselbrink et al. · Science Translational Medicine · 2016 · 549 citations

Medicine, Pharmacology, Clinical Pharmacology +8

Rectal Organoids Enable Personalized Treatment of Cystic Fibrosis

Gitte Berkers, Peter van Mourik, Annelotte M. Vonk et al. · Cell Reports · 2019 · 310 citations · Full text

Medicine, Cell Biology, Pharmacology +16

CRISPR-Based Adenine Editors Correct Nonsense Mutations in a Cystic Fibrosis Organoid Biobank

Maarten H. Geurts, Eyleen de Poel, Gimano D. Amatngalim et al. · Cell stem cell · 2020 · 220 citations · Full text

Life Sciences, Genetics, Molecular Genetics +12