Hugo R. de Jonge

A functional CFTR assay using primary cystic fibrosis intestinal organoids

Johanna F. Dekkers, Caroline L. Wiegerinck, Hugo R. de Jonge et al. · Nature Medicine · 2013 · 977 citations

Inflammation, Fibrosis, Immunology +6

Characterizing responses to CFTR-modulating drugs using rectal organoids derived from subjects with cystic fibrosis

Johanna F. Dekkers, Gitte Berkers, Evelien Kruisselbrink et al. · Science Translational Medicine · 2016 · 539 citations

Differential roles of NHERF1, NHERF2, and PDZK1 in regulating CFTR-mediated intestinal anion secretion in mice

Anurag Kumar Singh, Brigitte Riederer, Anja Krabbenhöft et al. · Journal of Clinical Investigation · 2009 · 359 citations · Full text

Immunology, Differential Roles, Cellular Physiology +21

Rectal Organoids Enable Personalized Treatment of Cystic Fibrosis

Gitte Berkers, Peter van Mourik, Annelotte M. Vonk et al. · Cell Reports · 2019 · 300 citations · Full text

Protein tyrosine phosphorylation is involved in osmoregulation of ionic conductances.

Ben C. Tilly, N van den Berghe, Leon G.J. Tertoolen et al. · Journal of Biological Chemistry · 1993 · 212 citations · Full text

Tyrosine Kinase, Cellular Physiology, Human Intestine 407 +19