Concepedia

One-Atom Substitution Enables Direct and Continuous Monitoring of Histone Deacylase Activity

Matthes Zessin, Zsófia Kutil, Marat Meleshin, Zora Nováková, Ehab Ghazy, Diana Kalbas, Martin Marek, Christophe Romier, Wolfgang Sippl, Cyril Bařinka,

Biochemistry · 2019 · 45 citations · 124 references

DOI

Concepts

Abstract

value of 1 μM for an N-methylated, N-myristoylated peptide derivative and human HDAC11.

References

124

A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

Ji-Hu Zhang, Thomas D.Y. Chung, Kevin R. Oldenburg · SLAS DISCOVERY · 1999 · 7K citations · Full text

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Identification of 67 Histone Marks and Histone Lysine Crotonylation as a New Type of Histone Modification

Minjia Tan, Hao Luo, Sangkyu Lee et al. · Cell · 2011 · 1.9K citations · Full text

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A Mammalian Histone Deacetylase Related to the Yeast Transcriptional Regulator Rpd3p

Jack Taunton, Christian A. Hassig, Stuart L. Schreiber · Science · 1996 · 1.8K citations

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Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes

Jill C. Milne, Philip Lambert, Simon Schenk et al. · Nature · 2007 · 1.7K citations · Full text

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Sirt5 Is a NAD-Dependent Protein Lysine Demalonylase and Desuccinylase

Jintang Du, Yeyun Zhou, Xiaoyang Su et al. · Science · 2011 · 1.4K citations · Full text

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