Simon Schenk

Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes

Jill C. Milne, Philip Lambert, Simon Schenk et al. · Nature · 2007 · 1.7K citations · Full text

Diabetes Management, Medicine, Diabetes +9

Increased Adipocyte O2 Consumption Triggers HIF-1α, Causing Inflammation and Insulin Resistance in Obesity

Yun Sok Lee, Jung‐whan Kim, Olivia Osborne et al. · Cell · 2014 · 559 citations · Full text

Insulin Resistance, Metabolic Syndrome, Obesity +12

A fasting inducible switch modulates gluconeogenesis via activator/coactivator exchange

Yi Liu, Renaud Dentin, Danica Chen et al. · Nature · 2008 · 538 citations · Full text

Signal Transduction, Activator/coactivator Exchange, G Protein-coupled Receptor +4

Hematopoietic Cell-Specific Deletion of Toll-like Receptor 4 Ameliorates Hepatic and Adipose Tissue Insulin Resistance in High-Fat-Fed Mice

Maziyar Saberi, Niels-Bjarne Woods, Carl de Luca et al. · Cell Metabolism · 2009 · 435 citations · Full text

Obesity, Metabolic Syndrome, Inflammation +14

SIRT1 inhibits inflammatory pathways in macrophages and modulates insulin sensitivity

Takeshi Yoshizaki, Simon Schenk, Takeshi Imamura et al. · American Journal of Physiology-Endocrinology and Metabolism · 2009 · 417 citations