Cryptochrome mediates circadian regulation of cAMP signaling and hepatic gluconeogenesis

Eric Erquan Zhang, Yi Liu, Renaud Dentin, +10

Nature Medicine

Energy HomeostasisSignal TransductionCamp SignalingMedicinePhysiology +9

A fasting inducible switch modulates gluconeogenesis via activator/coactivator exchange

Yi Liu, Renaud Dentin, Danica Chen, +10

Nature

Signal TransductionActivator/coactivator ExchangeG Protein-coupled ReceptorPhysiologyMedicine +2

Hepatic Glucokinase Is Required for the Synergistic Action of ChREBP and SREBP-1c on Glycolytic and Lipogenic Gene Expression

Renaud Dentin, Jean‐Paul Pégorier, Fadila Benhamed, +6

Journal of Biological Chemistry

Synergistic ActionFatty Liver DiseaseInsulin SignalingMetabolic SyndromeProtein Expression +19

Liver-Specific Inhibition of ChREBP Improves Hepatic Steatosis and Insulin Resistance in <i>ob/ob</i> Mice

Renaud Dentin, Fadila Benhamed, Isabelle Hainault, +5

Diabetes

Short Hairpin RnasFatty Liver DiseaseInsulin SignalingObesityMetabolic Syndrome +21

Insulin modulates gluconeogenesis by inhibition of the coactivator TORC2

Renaud Dentin, Yi Liu, Seung‐Hoi Koo, +5

Nature

Metabolic SyndromeInsulin SignalingBiochemistryMedicineInsulin Management +8

Polyunsaturated fatty acids suppress glycolytic and lipogenic genes through the inhibition of ChREBP nuclear protein translocation

Renaud Dentin

Journal of Clinical Investigation

Metabolic PathwaysFatty Acids SuppressLipid MetabolismBiochemistryFatty Acids +11

Hepatic Glucose Sensing via the CREB Coactivator CRTC2

Renaud Dentin, Susan Hedrick, Jianxin Xie, +2

Science

Salt-inducible kinase 2 links transcriptional coactivator p300 phosphorylation to the prevention of ChREBP-dependent hepatic steatosis in mice

Julien Bricambert, Jonatan Miranda, Fadila Benhamed, +3

Journal of Clinical Investigation

Chrebp-dependent Hepatic SteatosisFatty Liver DiseaseInsulin SignalingMetabolic SyndromeTranscriptional Regulation +19

Adipocyte CREB Promotes Insulin Resistance in Obesity

Ling Qi, Maziyar Saberi, Erik Zmuda, +9

Cell Metabolism

ObesityMetabolic SyndromeDiabetesPhysiologyMetabolic Regulation +4

<i>O</i>-GlcNAcylation Increases ChREBP Protein Content and Transcriptional Activity in the Liver

Céline Guinez, Gaëlle Filhoulaud, Fadila Rayah‐Benhamed, +9

Diabetes