Concepedia

Substrate Specificity

Substrate Specificity is the inherent property of an enzyme that determines the selective recognition and binding of a particular substrate over other potential substrates, distinguishing it from related catalytic activities within the broader class of enzyme–substrate interactions.

5K

Publications

276.3K

Citations

16.2K

Authors

2.3K

Institutions

Publications per year

2017–2026

380

Parents

Children

Publications

5K

Application of a Theory of Enzyme Specificity to Protein Synthesis

Daniel E. Koshland · Proceedings of the National Academy of Sciences · 1958 · 2.4K citations · Full text

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Substrate-inducible Microsomal Aryl Hydroxylase in Mammalian Cell Culture

Daniel W. Nebert, Harry V. Gelboin · Journal of Biological Chemistry · 1968 · 1.7K citations · Full text

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Defining the Human Deubiquitinating Enzyme Interaction Landscape

Mathew E. Sowa, Eric J. Bennett, Steven P. Gygi et al. · Cell · 2009 · 1.6K citations · Full text

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Consensus sequences as substrate specificity determinants for protein kinases and protein phosphatases

Peter J. Kennelly, E G Krebs · Journal of Biological Chemistry · 1991 · 1.3K citations · Full text

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Substrate recognition sites in cytochrome P450 family 2 (CYP2) proteins inferred from comparative analyses of amino acid and coding nucleotide sequences.

Osamu Gotoh · Journal of Biological Chemistry · 1992 · 1.2K citations · Full text

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1–5 of 5K

Authors

16.2K

  1. CS
    Charles S. Craik

    University of California, San Francisco, United States

    18 publications · 1.8K citations

    17

    h-index

  2. WJ
    William J. Rutter

    University of California, San Francisco, United States

    17 publications · 2.2K citations

    15

    h-index

  3. HR
    H. Ronald Kaback

    University of California, Los Angeles, United States

    15 publications · 936 citations

    15

    h-index

  4. AM
    Alexander M. Klibanov

    Massachusetts Institute of Technology, United States

    15 publications · 2.8K citations

    14

    h-index

  5. HN
    Hans Neurath

    University of Washington, United States

    15 publications · 998 citations

    14

    h-index

1–5 of 16.2K

Institutions

2.3K

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    46 h-index

    169 publications

    21.6K citations

  2. University of California, San Francisco

    San Francisco, United States

    43 h-index

    182 publications

    17.3K citations

  3. National Institutes of Health

    Bethesda, United States

    38 h-index

    173 publications

    16.6K citations

  4. Centre National de la Recherche Scientifique

    Paris, France

    38 h-index

    234 publications

    15.2K citations

  5. Harvard University

    Cambridge, United States

    37 h-index

    144 publications

    20.3K citations

  6. University of Michigan

    Ann Arbor, United States

    34 h-index

    206 publications

    14.5K citations

  7. Johns Hopkins University

    Baltimore, United States

    31 h-index

    111 publications

    9.7K citations

  8. Massachusetts Institute of Technology

    Cambridge, United States

    28 h-index

    87 publications

    9.4K citations

1–8 of 2.3K

Venues

  1. Journal of Biological Chemistry

    JBC · 614 publications · 47.7K citations

    102

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  2. Biochemistry

    796 publications · 42.9K citations

    96

    h-index

  3. Journal of the American Chemical Society

    JACS · 211 publications · 14.9K citations

    67

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 108 publications · 14.8K citations

    61

    h-index

  5. European Journal of Biochemistry

    EJB · 148 publications · 8.1K citations

    48

    h-index

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