Concepedia

Kinetic Specificity

Kinetic Specificity is a biochemical parameter that quantifies the preference of an enzyme for one substrate over another by measuring the ratio of catalytic efficiency (kcat/Km) for competing substrates under steady-state conditions.

351

Publications

19.6K

Citations

1.3K

Authors

422

Institutions

Publications per year

2017–2026

25

Parents

Publications

351

Kinetic Proofreading: A New Mechanism for Reducing Errors in Biosynthetic Processes Requiring High Specificity

J. J. Hopfield · Proceedings of the National Academy of Sciences · 1974 · 1.6K citations · Full text

, , +14

A Kinetic Study of Pyrophosphate: Fructose‐6‐Phosphate Phosphotransferase from Potato Tubers

Emile Van Schaftingen, B Lederer, Ramón Bartrons et al. · European Journal of Biochemistry · 1982 · 660 citations · Full text

, , +12

Kinetic Basis for DNA Target Specificity of CRISPR-Cas12a

Isabel Strohkendl, Fatema A. Saifuddin, James R. Rybarski et al. · Molecular Cell · 2018 · 345 citations · Full text

, , +11

Interfacial Kinetic and Binding Properties of the Complete Set of Human and Mouse Groups I, II, V, X, and XII Secreted Phospholipases A2

Alan G. Singer, Farideh Ghomashchi, Catherine Le Calvez et al. · Journal of Biological Chemistry · 2002 · 329 citations · Full text

, , +17

Catalytic efficiency and kcat/KM: a useful comparator?

Robert Eisenthal, Michael J. Danson, David W. Hough · Trends in biotechnology · 2007 · 316 citations

, , +10

1–5 of 351

Authors

1.3K

  1. RL
    Ross L. Stein

    Harvard University, United States

    4 publications · 203 citations

    4

    h-index

  2. FG
    Francisco Garcı́a-Cánovas

    Universidad de Murcia, Spain

    4 publications · 299 citations

    4

    h-index

  3. PA
    Philip A. Cole

    Johns Hopkins University, United States

    3 publications · 268 citations

    3

    h-index

  4. KB
    K Brocklehurst

    St Bartholomew's Hospital, United Kingdom

    3 publications · 78 citations

    3

    h-index

  5. JS
    John S. Blanchard

    Albert Einstein College of Medicine, United States

    3 publications · 162 citations

    3

    h-index

1–5 of 1.3K

Institutions

422

  1. Centre National de la Recherche Scientifique

    Paris, France

    13 h-index

    48 publications

    3.8K citations

  2. University of Wisconsin–Madison

    Madison, United States

    7 h-index

    18 publications

    1.7K citations

  3. Albert Einstein College of Medicine

    Bronx, United States

    6 h-index

    21 publications

    1.9K citations

  4. National Institutes of Health

    Bethesda, United States

    5 h-index

    17 publications

    1.4K citations

  5. University of Michigan

    Ann Arbor, United States

    5 h-index

    12 publications

    389 citations

  6. Universidade de São Paulo

    São Paulo, Brazil

    5 h-index

    13 publications

    387 citations

  7. University of Guelph

    Guelph, Canada

    4 h-index

    10 publications

    288 citations

  8. Universidad de Murcia

    Murcia, Spain

    4 h-index

    21 publications

    1.5K citations

1–8 of 422

Venues

  1. Biochemistry

    62 publications · 4.1K citations

    38

    h-index

  2. Journal of Biological Chemistry

    JBC · 44 publications · 2.7K citations

    32

    h-index

  3. Biochemical Journal

    BJ · 24 publications · 1.1K citations

    19

    h-index

  4. European Journal of Biochemistry

    EJB · 17 publications · 1.9K citations

    16

    h-index

  5. Archives of Biochemistry and Biophysics

    ABB · 11 publications · 494 citations

    11

    h-index

1–5