Ji-Hu Zhang

A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

Ji-Hu Zhang, Thomas D.Y. Chung, Kevin R. Oldenburg · SLAS DISCOVERY · 1999 · 6.9K citations · Full text

Allosteric inhibition of SHP2 phosphatase inhibits cancers driven by receptor tyrosine kinases

Ying-Nan P. Chen, Matthew J. LaMarche, Ho Man Chan et al. · Nature · 2016 · 893 citations

Cancer Research, Allosteric Inhibition, Signal Transduction +12

Selective inhibition of Ezh2 by a small molecule inhibitor blocks tumor cells proliferation

Wei Qi, Homan Chan, Lin Teng et al. · Proceedings of the National Academy of Sciences · 2012 · 542 citations · Full text

Selective Inhibition, Tumor Biology, Methyl Group +15

Allosteric Inhibition of SHP2: Identification of a Potent, Selective, and Orally Efficacious Phosphatase Inhibitor

Jorge Fortanet, Christine Hiu-Tung Chen, Ying-Nan P. Chen et al. · Journal of Medicinal Chemistry · 2016 · 284 citations · Full text

Allosteric Inhibition, Drug Target, Shp2 Inhibition +20

Directed evolution of a fucosidase from a galactosidase by DNA shuffling and screening

Ji-Hu Zhang, Glenn Dawes, Willem P.C. Stemmer · Proceedings of the National Academy of Sciences · 1997 · 275 citations · Full text