Concepedia

Enzyme-substrate Recognition

Enzyme-Substrate Recognition is the specific molecular interaction in which an enzyme selectively binds its substrate through complementary structural and chemical features, enabling catalytic transformation.

34K

Publications

1.8M

Citations

95.8K

Authors

7.3K

Institutions

Publications per year

2017–2026

5.7K

Variants

Enzyme - Substrate Recognition

Parents

Children

Publications

34K

Proline-Catalyzed Direct Asymmetric Aldol Reactions

Benjamin List, Richard A. Lerner, Carlos F. Barbas · Journal of the American Chemical Society · 2000 · 2.8K citations

, , +10

Nitric oxide synthases: structure, function and inhibition

W. Alderton, Chris E. Cooper, Richard G. Knowles · Biochemical Journal · 2001 · 2.7K citations

, , +17

Application of a Theory of Enzyme Specificity to Protein Synthesis

Daniel E. Koshland · Proceedings of the National Academy of Sciences · 1958 · 2.4K citations · Full text

, , +14

Hybrid restriction enzymes: zinc finger fusions to Fok I cleavage domain.

Y G Kim, Srinivasan Chandrasegaran · Proceedings of the National Academy of Sciences · 1996 · 2.1K citations

, , +15

Structure and energetics of ligand binding to proteins: <i>Escherichia coli</i> dihydrofolate reductase‐trimethoprim, a drug‐receptor system

Pnina Dauber‐Osguthorpe, Victoria A. Roberts, David J. Osguthorpe et al. · Proteins Structure Function and Bioinformatics · 1988 · 2.1K citations

, , +16

1–5 of 34K

Authors

95.8K

  1. CT
    Christopher T. Walsh

    Harvard University, United States

    85 publications · 7.6K citations

    48

    h-index

  2. DE
    David E. Cane

    Brown University, United States

    67 publications · 5.3K citations

    46

    h-index

  3. RH
    Robert Huber

    Max Planck Institute of Biochemistry, Germany

    58 publications · 6K citations

    42

    h-index

  4. CK
    Chaitan Khosla

    Stanford University, United States

    58 publications · 5.5K citations

    42

    h-index

  5. DW
    David W. Christianson

    University of Pennsylvania, United States

    56 publications · 4.7K citations

    41

    h-index

1–5 of 95.8K

Institutions

7.3K

  1. Centre National de la Recherche Scientifique

    Paris, France

    111 h-index

    4.3K publications

    235.4K citations

  2. Harvard University

    Cambridge, United States

    108 h-index

    1.3K publications

    168.3K citations

  3. Howard Hughes Medical Institute

    Chevy Chase, United States

    108 h-index

    1.2K publications

    116.1K citations

  4. Scripps Research Institute

    San Diego, United States

    91 h-index

    1.3K publications

    121.2K citations

  5. University of California, San Francisco

    San Francisco, United States

    85 h-index

    887 publications

    83.4K citations

  6. Chinese Academy of Sciences

    Beijing, China

    81 h-index

    2.2K publications

    112.7K citations

  7. National Institutes of Health

    Bethesda, United States

    80 h-index

    1K publications

    69.6K citations

  8. University of California, Berkeley

    Berkeley, United States

    78 h-index

    899 publications

    69.3K citations

1–8 of 7.3K

Venues

  1. Journal of Biological Chemistry

    JBC · 3.5K publications · 225.4K citations

    171

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 929 publications · 102.9K citations

    161

    h-index

  3. Journal of the American Chemical Society

    JACS · 1.5K publications · 118.8K citations

    153

    h-index

  4. Biochemistry

    3.1K publications · 149.9K citations

    134

    h-index

  5. Journal of Molecular Biology

    JMB · 854 publications · 55.8K citations

    113

    h-index

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