Concepedia

Subsite Interactions

Subsite Interactions is a biochemical mechanism that specifies the non-covalent molecular contacts between defined regions of an enzyme's active site, known as subsites, and corresponding structural elements of the substrate, thereby conferring substrate specificity and catalytic efficiency in enzyme-substrate recognition.

82

Publications

5.6K

Citations

386

Authors

125

Institutions

Publications per year

2017–2026

6

Parents

Publications

82

Studies of the cellulolytic system of <i>Trichoderma reesei</i> QM 9414

Peter Tomme, Herman van Tilbeurgh, Göran Pettersson et al. · European Journal of Biochemistry · 1988 · 581 citations

, , +13

Binding of small molecules to an adaptive protein–protein interface

Michelle R. Arkin, Mike Randal, Warren L. DeLano et al. · Proceedings of the National Academy of Sciences · 2003 · 380 citations

, , +17

The metabolism of neuropeptides. The hydrolysis of peptides, including enkephalins, tachykinins and their analogues, by endopeptidase-24.11

Rebecca Matsas, A J Kenny, Anthony J. Turner · Biochemical Journal · 1984 · 374 citations

, , +14

Internally quenched fluorescent peptide substrates disclose the subsite preferences of human caspases 1, 3, 6, 7 and 8

Henning R. Stennicke, Martin Renatus, Morten Meldal et al. · Biochemical Journal · 2000 · 309 citations · Full text

, , +17

Bacterial promoter architecture: subsite structure of UP elements and interactions with the carboxy-terminal domain of the RNA polymerase alpha subunit

Shawn T. Estrem, Wilma Ross, Tamás Gaál et al. · Genes & Development · 1999 · 211 citations · Full text

, , +17

1–5 of 82

Authors

386

  1. MC
    Marc Claeyssens

    Ghent University, Belgium

    3 publications · 698 citations

    3

    h-index

  2. VG
    Vincent G. H. Eijsink

    Norwegian University of Life Sciences, Norway

    3 publications · 162 citations

    3

    h-index

  3. HV
    Herman van Tilbeurgh

    Centre National de la Recherche Scientifique, France

    3 publications · 698 citations

    3

    h-index

  4. GP
    Göran Pettersson

    Uppsala University, Sweden

    2 publications · 657 citations

    2

    h-index

  5. BM
    Barbra M. Fisher

    University of Colorado Denver, United States

    2 publications · 131 citations

    2

    h-index

1–5 of 386

Institutions

125

  1. Sanford Burnham Prebys Medical Discovery Institute

    La Jolla, United States

    3 h-index

    9 publications

    1.7K citations

  2. The University of Tokyo

    Tokyo, Japan

    3 h-index

    11 publications

    199 citations

  3. University of Wisconsin–Madison

    Madison, United States

    3 h-index

    11 publications

    1.4K citations

  4. Carlsberg Laboratory

    Copenhagen, Denmark

    3 h-index

    3 publications

    415 citations

  5. National Yang Ming Chiao Tung University

    Hsinchu, Taiwan

    2 h-index

    6 publications

    138 citations

  6. Biotechnology Research Institute

    Montreal, Canada

    2 h-index

    10 publications

    546 citations

  7. National Taiwan University

    Taipei, Taiwan

    2 h-index

    7 publications

    492 citations

  8. VTT Technical Research Centre of Finland

    Espoo, Finland

    2 h-index

    3 publications

    1.2K citations

1–8 of 125

Venues

  1. Biochemistry

    17 publications · 855 citations

    15

    h-index

  2. Journal of Medicinal Chemistry

    10 publications · 436 citations

    10

    h-index

  3. Journal of Biological Chemistry

    JBC · 6 publications · 499 citations

    6

    h-index

  4. European Journal of Biochemistry

    EJB · 6 publications · 874 citations

    6

    h-index

  5. Biochemical Journal

    BJ · 6 publications · 1.1K citations

    6

    h-index

1–5