Concepedia

Transition State Recognition

Transition State Recognition is a biochemical mechanism by which an enzyme selectively binds and stabilizes the high-energy transition state of a substrate during catalysis, thereby distinguishing it from alternative substrate states and enhancing catalytic efficiency through complementarity in structure and charge distribution.

30

Publications

1.9K

Citations

103

Authors

60

Institutions

Publications per year

2017–2026

8

Parents

Publications

30

Atomic Structure of Adenosine Deaminase Complexed with a Transition-State Analog: Understanding Catalysis and Immunodeficiency Mutations

David K. Wilson, Frederick B. Rudolph, Florante A. Quiocho · Science · 1991 · 443 citations

, , +17

Anion−π Catalysis

Yingjie Zhao, César Beuchat, Yuya Domoto et al. · Journal of the American Chemical Society · 2014 · 191 citations · Full text

, , +17

Electric-Field-Assisted Anion−π Catalysis

Masaaki Akamatsu, Naomi Sakai, Stefan Matile · Journal of the American Chemical Society · 2017 · 132 citations · Full text

, , +17

A machine learning based personalized system for driving state recognition

Dewei Yi, Jinya Su, Cunjia Liu et al. · Transportation Research Part C Emerging Technologies · 2019 · 101 citations · Full text

, , +16

Enzyme catalysis: Conflicting requirements of substrate access and transition state affinity

Richard Wolfenden · Molecular and Cellular Biochemistry · 1974 · 91 citations

, , +17

1–5 of 30

Authors

103

  1. RW
    Richard Wolfenden

    University of North Carolina at Chapel Hill, United States

    3 publications · 172 citations

    3

    h-index

  2. SM
    Stefan Matile

    University of Geneva, Switzerland

    2 publications · 323 citations

    2

    h-index

  3. IH
    Ian H. Williams

    University of Bath, United Kingdom

    2 publications · 99 citations

    2

    h-index

  4. NS
    Naomi Sakai

    University of Geneva, Switzerland

    2 publications · 323 citations

    2

    h-index

  5. FW
    Frank Würthner

    University of Würzburg, Germany

    1 publications · 32 citations

    1

    h-index

1–5 of 103

Institutions

60

  1. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    3 h-index

    5 publications

    253 citations

  2. Bridge University

    Juba, South Sudan

    2 h-index

    3 publications

    183 citations

  3. University of Geneva

    Geneva, Switzerland

    2 h-index

    11 publications

    1.9K citations

  4. Baylor College of Medicine

    Houston, United States

    1 h-index

    2 publications

    886 citations

  5. Loughborough University

    Loughborough, United Kingdom

    1 h-index

    4 publications

    404 citations

  6. Discovery Centre

    Halifax, Canada

    1 h-index

    4 publications

    72 citations

  7. Universität Hamburg

    Hamburg, Germany

    1 h-index

    9 publications

    657 citations

  8. University of Freiburg

    Freiburg im Breisgau, Germany

    1 h-index

    2 publications

    156 citations

1–8 of 60

Venues

  1. Journal of the American Chemical Society

    JACS · 5 publications · 499 citations

    5

    h-index

  2. Science

    2 publications · 494 citations

    2

    h-index

  3. Journal of Molecular Biology

    JMB · 2 publications · 96 citations

    2

    h-index

  4. Biochemistry

    2 publications · 60 citations

    2

    h-index

  5. Beilstein Journal of Organic Chemistry

    BJOC · 1 publications · 14 citations

    1

    h-index

1–5