Concepedia

Activation of Caspase-6 Is Promoted by a Mutant Huntingtin Fragment and Blocked by an Allosteric Inhibitor Compound

Dagmar E. Ehrnhoefer, Niels H. Skotte, Jeanette Reinshagen, Xiaofan Qiu, Björn Windshügel, Priyadarshini Jaishankar, Safia Ladha, Olga A. Petina, Mehdi Khankischpur, Yen T.N. Nguyen,

Cell chemical biology · 2019 · 22 citations · 42 references

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42

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes

Marcy E. MacDonald · Cell · 1993 · 8.4K citations · Full text

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A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

Ji-Hu Zhang, Thomas D.Y. Chung, Kevin R. Oldenburg · SLAS DISCOVERY · 1999 · 7K citations · Full text

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A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. The Huntington's Disease Collaborative Research Group.

Manish A. Shah, Nicole A. Datson, Lakshmi Srinidhi et al. · Cell · 1993 · 3.1K citations

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Trinucleotide repeat length instability and age of onset in Huntington's disease

Mabel P. Duyao, C M Ambrose, Richard H. Myers et al. · Nature Genetics · 1993 · 1.1K citations

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Cleavage at the Caspase-6 Site Is Required for Neuronal Dysfunction and Degeneration Due to Mutant Huntingtin

Rona K. Graham, Yu Deng, Elizabeth Slow et al. · Cell · 2006 · 649 citations · Full text

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