Caspase Cleavage is a proteolytic process in which caspases, a family of cysteine-aspartic proteases, selectively cleave target proteins at specific aspartic acid residues to initiate or execute programmed cell death.
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Cleavage of BID by Caspase 8 Mediates the Mitochondrial Damage in the Fas Pathway of Apoptosis
Honglin Li, Hong Zhu, Chi-jie Xu et al. · Cell · 1998 · 4.4K citations · Full text
Molecular and Genetic Properties of Tumors Associated with Local Immune Cytolytic Activity
Michael S. Rooney, Sachet A. Shukla, Catherine J. Wu et al. · Cell · 2015 · 4.1K citations · Full text
Medicine, Immunology, Oncology +17
Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling
Nobuhiko Kayagaki, Irma B. Stowe, Bettina L. Lee et al. · Nature · 2015 · 3.7K citations
A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD
Masato Enari, Hideki Sakahira, Hideki Yokoyama et al. · Nature · 1998 · 3.2K citations
1–5 of 6.2K
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31.9K
- GSGuy S. Salvesen
Sanford Burnham Prebys Medical Discovery Institute, United States
62 publications · 19.9K citations
49
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- PV
34
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- DW
32
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- DRDouglas R. Green
St. Jude Children's Research Hospital, United States
28 publications · 12.5K citations
28
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- MR
24
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1–5 of 31.9K
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4.5K
Harvard University
Cambridge, United States
70 h-index
525 publications
122.1K citations
Sanford Burnham Prebys Medical Discovery Institute
La Jolla, United States
63 h-index
335 publications
105.3K citations
Massachusetts General Hospital
Boston, United States
51 h-index
275 publications
57.6K citations
Inserm
Paris, France
50 h-index
624 publications
33K citations
Howard Hughes Medical Institute
Chevy Chase, United States
46 h-index
162 publications
43.9K citations
National Institutes of Health
Bethesda, United States
46 h-index
271 publications
39.6K citations
Centre National de la Recherche Scientifique
Paris, France
43 h-index
355 publications
21.2K citations
Johns Hopkins University
Baltimore, United States
41 h-index
238 publications
28.8K citations
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- Journal of Biological Chemistry
JBC · 488 publications · 74.6K citations
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- Proceedings of the National Academy of Sciences
PNAS · 113 publications · 20.2K citations
81
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- PubMed
Repository · 246 publications · 15.7K citations
68
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- Cell Death and Differentiation
CDD · 102 publications · 8.7K citations
52
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- The Journal of Immunology
JI · 90 publications · 7.5K citations
52
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