Hideki Sakahira

A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD

Masato Enari, Hideki Sakahira, Hideki Yokoyama et al. · Nature · 1998 · 3.2K citations

Caspase-activated Dnase, Natural Sciences, Apoptosis +8

Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis

Hideki Sakahira, Masato Enari, Shigekazu Nagata · Nature · 1998 · 1.6K citations

Apoptosis, Cell Death, Anti-cancer Agent +8

Cellular Toxicity of Polyglutamine Expansion Proteins

Gregor Schaffar, Péter Breuer, Raina Boteva et al. · Molecular Cell · 2004 · 424 citations · Full text

Neurodegenerative Diseases, Protein Function, Intraneural Inclusions +12

An auxiliary mode of apoptotic DNA fragmentation provided by phagocytes

Dorian McIlroy, Masato Tanaka, Hideki Sakahira et al. · Genes & Development · 2000 · 189 citations · Full text

Genome Instability, Auxiliary Mode, Cell Regulation +15

Molecular cloning and characterization of human caspase-activated DNase

Naomi Mukae, Masato Enari, Hideki Sakahira et al. · Proceedings of the National Academy of Sciences · 1998 · 172 citations · Full text

Cad Mrna, Genome Instability, Protein Expression +14