Shigekazu Nagata

A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD

Masato Enari, Hideki Sakahira, Hideki Yokoyama et al. · Nature · 1998 · 3.2K citations

Caspase-activated Dnase, Natural Sciences, Apoptosis +8

Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis

Rie Watanabe‐Fukunaga, Camilynn I. Brannan, Neal G. Copeland et al. · Nature · 1992 · 2.9K citations

Lymphoproliferation Disorder, Knockout Mouse, Autoimmune Disease +12

The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis

Naoto Itoh, Shin Yonehara, Ai Ishii et al. · Cell · 1991 · 2.8K citations

Molecular Immunology, Apoptosis, Immunology +9

Molecular cloning and expression of the fas ligand, a novel member of the tumor necrosis factor family

Takashi Suda, Tomohiro Takahashi, Pierre Golstein et al. · Cell · 1993 · 2.5K citations

Inflammation, Signal Transduction, Disease Mechanism +10

Lethal effect of the anti-Fas antibody in mice

Jun Ogasawara, Rie Watanabe‐Fukunaga, Masashi Adachi et al. · Nature · 1993 · 1.9K citations

Autoimmune Disease, Immunology, Lethal Effect +7