Gregor Schaffar

Hsp70 and Hsp40 chaperones can inhibit self-assembly of polyglutamine proteins into amyloid-like fibrils

Paul J. Muchowski, Gregor Schaffar, Annie Sittler et al. · Proceedings of the National Academy of Sciences · 2000 · 669 citations · Full text

Protein Assembly, Molecular Biology, Protein Phase Separation +18

Cellular Toxicity of Polyglutamine Expansion Proteins

Gregor Schaffar, Péter Breuer, Raina Boteva et al. · Molecular Cell · 2004 · 424 citations · Full text

Neurodegenerative Diseases, Protein Function, Intraneural Inclusions +12

Chaperonin TRiC Promotes the Assembly of polyQ Expansion Proteins into Nontoxic Oligomers

Christian Behrends, C.A. Langer, Raina Boteva et al. · Molecular Cell · 2006 · 280 citations · Full text

Studying interactions of four proteins in the yeast two-hybrid system: Structural resemblance of the pVHL/elongin BC/hCUL-2 complex with the ubiquitin ligase complex SKP1/cullin/F-box protein

Arnim Pause, Brett S. Peterson, Gregor Schaffar et al. · Proceedings of the National Academy of Sciences · 1999 · 98 citations · Full text

Single particle detection and characterization of synuclein co-aggregation

Armin Giese, Benedikt Bader, Jan Bieschke et al. · Biochemical and Biophysical Research Communications · 2005 · 46 citations

Bioanalysis, Molecular Biology, Single Molecule +4