Niels H. Skotte

Potent and Selective Antisense Oligonucleotides Targeting Single-Nucleotide Polymorphisms in the Huntington Disease Gene / Allele-Specific Silencing of Mutant Huntingtin

Jeffrey B. Carroll, Simon C. Warby, Amber L. Southwell et al. · Molecular Therapy · 2011 · 287 citations · Full text

Site-specific characterization of endogenous SUMOylation across species and organs

Ivo A. Hendriks, David Lyon, Dan Su et al. · Nature Communications · 2018 · 227 citations · Full text

Rational design of antisense oligonucleotides targeting single nucleotide polymorphisms for potent and allele selective suppression of mutant Huntingtin in the CNS

Michael E. Østergaard, Amber L. Southwell, Holly Kordasiewicz et al. · Nucleic Acids Research · 2013 · 158 citations · Full text

In Vivo Evaluation of Candidate Allele-specific Mutant Huntingtin Gene Silencing Antisense Oligonucleotides

Amber L. Southwell, Niels H. Skotte, Holly Kordasiewicz et al. · Molecular Therapy · 2014 · 145 citations · Full text

Huntingtin suppression restores cognitive function in a mouse model of Huntington’s disease

Amber L. Southwell, Holly Kordasiewicz, Douglas R. Langbehn et al. · Science Translational Medicine · 2018 · 122 citations