Michael E. Østergaard

Stabilin-1 and Stabilin-2 are specific receptors for the cellular internalization of phosphorothioate-modified antisense oligonucleotides (ASOs) in the liver

Colton M. Miller, Aaron J. Donner, Emma E Blank et al. · Nucleic Acids Research · 2016 · 164 citations · Full text

Life Sciences, Cell Biology, Pharmacology +15

Rational design of antisense oligonucleotides targeting single nucleotide polymorphisms for potent and allele selective suppression of mutant Huntingtin in the CNS

Michael E. Østergaard, Amber L. Southwell, Holly Kordasiewicz et al. · Nucleic Acids Research · 2013 · 162 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Fatty acid conjugation enhances potency of antisense oligonucleotides in muscle

Thazha P. Prakash, Adam E. Mullick, Richard Lee et al. · Nucleic Acids Research · 2019 · 154 citations · Full text

Life Sciences, Biochemistry, Pharmacology +15

In Vivo Evaluation of Candidate Allele-specific Mutant Huntingtin Gene Silencing Antisense Oligonucleotides

Amber L. Southwell, Niels H. Skotte, Holly Kordasiewicz et al. · Molecular Therapy · 2014 · 148 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Characterization of the interactions of chemically-modified therapeutic nucleic acids with plasma proteins using a fluorescence polarization assay

Hans Gaus, Ruchi Gupta, Alfred E. Chappell et al. · Nucleic Acids Research · 2018 · 143 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17