Michael E. Østergaard

Stabilin-1 and Stabilin-2 are specific receptors for the cellular internalization of phosphorothioate-modified antisense oligonucleotides (ASOs) in the liver

Colton M. Miller, Aaron J. Donner, Emma E Blank et al. · Nucleic Acids Research · 2016 · 162 citations · Full text

Molecular Biology, Internalization Rates, Stabilin Class +23

Rational design of antisense oligonucleotides targeting single nucleotide polymorphisms for potent and allele selective suppression of mutant Huntingtin in the CNS

Michael E. Østergaard, Amber L. Southwell, Holly Kordasiewicz et al. · Nucleic Acids Research · 2013 · 158 citations · Full text

In Vivo Evaluation of Candidate Allele-specific Mutant Huntingtin Gene Silencing Antisense Oligonucleotides

Amber L. Southwell, Niels H. Skotte, Holly Kordasiewicz et al. · Molecular Therapy · 2014 · 145 citations · Full text

Fatty acid conjugation enhances potency of antisense oligonucleotides in muscle

Thazha P. Prakash, Adam E. Mullick, Richard Lee et al. · Nucleic Acids Research · 2019 · 142 citations · Full text

Characterization of the interactions of chemically-modified therapeutic nucleic acids with plasma proteins using a fluorescence polarization assay

Hans Gaus, Ruchi Gupta, Alfred E. Chappell et al. · Nucleic Acids Research · 2018 · 138 citations · Full text

Molecular Biology, Nucleic Acid Biomarkers, Protein Purification +19