Ruchi Gupta

Two-dimensional IR spectroscopy and isotope labeling defines the pathway of amyloid formation with residue-specific resolution

Sang‐Hee Shim, Ruchi Gupta, Yun L. Ling et al. · Proceedings of the National Academy of Sciences · 2009 · 289 citations · Full text

Aromatic Interactions Are Not Required for Amyloid Fibril Formation by Islet Amyloid Polypeptide but Do Influence the Rate of Fibril Formation and Fibril Morphology

Peter Marek, Andisheh Abedini, Benben Song et al. · Biochemistry · 2007 · 138 citations

Characterization of the interactions of chemically-modified therapeutic nucleic acids with plasma proteins using a fluorescence polarization assay

Hans Gaus, Ruchi Gupta, Alfred E. Chappell et al. · Nucleic Acids Research · 2018 · 138 citations · Full text

Molecular Biology, Nucleic Acid Biomarkers, Protein Purification +19

Site-specific replacement of phosphorothioate with alkyl phosphonate linkages enhances the therapeutic profile of gapmer ASOs by modulating interactions with cellular proteins

Michael T. Migawa, Wen Shen, Wei Wan et al. · Nucleic Acids Research · 2019 · 119 citations · Full text

Signal Transduction, Biochemistry, Site-specific Replacement +11

Strategies for Extracting Structural Information from 2D IR Spectroscopy of Amyloid: Application to Islet Amyloid Polypeptide

David B. Strasfeld, Yun L. Ling, Ruchi Gupta et al. · The Journal of Physical Chemistry B · 2009 · 99 citations · Full text