Concepedia

Suppressing Mitochondrial Respiration Is Critical for Hypoxia Tolerance in the Fetal Growth Plate

Qing Yao, Mohd Parvez Khan, Christophe Merceron, Edward L. LaGory, Zachary Tata, Laura Mangiavini, Jiarui Hu, Krishna C. Vemulapalli, Navdeep S. Chandel, Amato J. Giaccia,

Developmental Cell · 2019 · 70 citations · 45 references

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45

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

Kenneth J. Livak, Thomas D. Schmittgen · Methods · 2001 · 181.5K citations

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Mutation of the mouse klotho gene leads to a syndrome resembling ageing.

PubMed · 1997 · 66.6K citations

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HIF-1-mediated expression of pyruvate dehydrogenase kinase: A metabolic switch required for cellular adaptation to hypoxia

Jung‐whan Kim, Irina Tchernyshyov, Gregg L. Semenza et al. · Cell Metabolism · 2006 · 3.9K citations · Full text

, , +17

Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours

Thomas G. Graeber, Cynthia Osmanian, Tyler Jacks et al. · Nature · 1996 · 2.3K citations

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HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption

Ioanna Papandreou, Rob A. Cairns, Lucrezia Fontana et al. · Cell Metabolism · 2006 · 2.2K citations · Full text

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