Tyler Jacks

MicroRNA expression profiles classify human cancers

Jun Lü, Gad Getz, Eric A. Miska et al. · Nature · 2005 · 9.5K citations

Pathology, Cancer Genomics, Microrna Expression Profiles +6

Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals

Mitchell Guttman, Ido Amit, Manuel Garber et al. · Nature · 2009 · 4.2K citations · Full text

Chromatin, Systems Biology, Large Non-coding Rnas +12

Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1

David A. Barbie, Pablo Tamayo, Jesse S. Boehm et al. · Nature · 2009 · 4.1K citations · Full text

Systems Biology, Oncogenic Agent, Medicine +4

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

Michael B. Kastan, Qimin Zhan, Wafik S. El‐Deiry et al. · Cell · 1992 · 3.1K citations

Genome Instability, Cell Regulation, Cell Death +5

p53-dependent apoptosis modulates the cytotoxicity of anticancer agents

Scott W. Lowe, H. Earl Ruley, Tyler Jacks et al. · Cell · 1993 · 2.9K citations

P53-dependent Apoptosis, Medicine, Apoptosis +6