Michael B. Kastan

Participation of p53 protein in the cellular response to DNA damage.

Michael B. Kastan, Onyinye Onyekwere, D Sidransky et al. · PubMed · 1991 · 3.8K citations

Life Sciences, Cell Biology, Molecular Biology +14

DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

Christopher J. Bakkenist, Michael B. Kastan · Nature · 2003 · 3.4K citations

Life Sciences, Biochemistry, Molecular Biology +15

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

Michael B. Kastan, Qimin Zhan, Wafik S. El‐Deiry et al. · Cell · 1992 · 3.1K citations

Life Sciences, Cell Biology, Molecular Biology +12

Activation of the ATM Kinase by Ionizing Radiation and Phosphorylation of p53

Christine E. Canman, Dae‐Sik Lim, Karlene A. Cimprich et al. · Science · 1998 · 2.1K citations

Medicine, Genetics, Oncology +15

Wild-type p53 is a cell cycle checkpoint determinant following irradiation.

Steven J. Kuerbitz, Beverly Plunkett, William Walsh et al. · Proceedings of the National Academy of Sciences · 1992 · 1.9K citations

Medicine, Cell Biology, Oncology +15