Karlene A. Cimprich

Activation of the ATM Kinase by Ionizing Radiation and Phosphorylation of p53

Christine E. Canman, Dae‐Sik Lim, Karlene A. Cimprich et al. · Science · 1998 · 2.1K citations

Medicine, Genetics, Oncology +15

Functional uncoupling of MCM helicase and DNA polymerase activities activates the ATR-dependent checkpoint

Tony Byun, Marcin Pacek, Muh‐Ching Yee et al. · Genes & Development · 2005 · 757 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Transcription-Replication Conflict Orientation Modulates R-Loop Levels and Activates Distinct DNA Damage Responses

Stephan Hamperl, M Bocek, Joshua C. Saldivar et al. · Cell · 2017 · 677 citations · Full text

Life Sciences, Genetics, Molecular Biology +12

Transcription-Coupled Nucleotide Excision Repair Factors Promote R-Loop-Induced Genome Instability

Julie Sollier, Caroline Townsend Stork, María García‐Rubio et al. · Molecular Cell · 2014 · 594 citations · Full text

Life Sciences, Genetics, Molecular Biology +10

A Genome-wide siRNA Screen Reveals Diverse Cellular Processes and Pathways that Mediate Genome Stability

Renee D. Paulsen, Deena V. Soni, Roy Wollman et al. · Molecular Cell · 2009 · 570 citations · Full text

Life Sciences, Genetics, Molecular Biology +12