Concepedia

Christopher J. Bakkenist

CJ

Statistics

Publications

56

Citations

8K

H-Index

36

Active since

1994

Affiliations

University of Pittsburgh(Current)

UPMC Hillman Cancer Center

University of Pittsburgh Medical Center

Inova Health System

St. Jude Children's Research Hospital

Christopher J. Bakkenist is an author at University of Pittsburgh specializing in life sciences, molecular biology, and dna damage signaling.

ORCID

Publications per year

1994–2023

56

Publications

56

DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

Christopher J. Bakkenist, Michael B. Kastan · Nature · 2003 · 3.4K citations

, , +15

Phosphorylation of SMC1 is a critical downstream event in the ATM–NBS1–BRCA1 pathway

Risa Kitagawa, Christopher J. Bakkenist, Peter J. McKinnon et al. · Genes & Development · 2004 · 538 citations · Full text

, , +17

The Telomeric Protein TRF2 Binds the ATM Kinase and Can Inhibit the ATM-Dependent DNA Damage Response

Jan Karlseder, Kristina Hoke, Olga K. Mirzoeva et al. · PLoS Biology · 2004 · 397 citations · Full text

, , +17

The orally active and bioavailable ATR kinase inhibitor AZD6738 potentiates the anti-tumor effects of cisplatin to resolve ATM-deficient non-small cell lung cancer<i>in vivo</i>

Frank P. Vendetti, Alan Lau, Sandra Schamus et al. · Oncotarget · 2015 · 244 citations · Full text

, , +16

ATR kinase inhibitor AZD6738 potentiates CD8+ T cell–dependent antitumor activity following radiation

Frank P. Vendetti, Pooja Karukonda, David A. Clump et al. · Journal of Clinical Investigation · 2018 · 209 citations · Full text

, , +17

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