Jan Karlseder

p53- and ATM-Dependent Apoptosis Induced by Telomeres Lacking TRF2

Jan Karlseder, Dominique Broccoli, Yumin Dai et al. · Science · 1999 · 1.1K citations

Chromatin, Genome Instability, Dna Damage +12

Mammalian Telomeres Resemble Fragile Sites and Require TRF1 for Efficient Replication

Agnel Sfeir, Settapong T Kosiyatrakul, Dirk Hockemeyer et al. · Cell · 2009 · 980 citations · Full text

Chromatin, Genome Instability, Efficient Replication +11

Senescence Induced by Altered Telomere State, Not Telomere Loss

Jan Karlseder, Agata Smogorzewska, Titia de Lange · Science · 2002 · 789 citations

Lifespan Extension, Chromatin, Genome Instability +14

Defective Telomere Lagging Strand Synthesis in Cells Lacking WRN Helicase Activity

Laure Crabbé, Ramiro E. Verdún, Candy Haggblom et al. · Science · 2004 · 595 citations

Chromatin, Genome Instability, Individual Telomeres +15

Autophagic cell death restricts chromosomal instability during replicative crisis

Joe Nassour, Robert J. Radford, Adriana Correia et al. · Nature · 2019 · 407 citations · Full text

Chromatin, Genome Instability, Mitophagy +6