p53- and ATM-Dependent Apoptosis Induced by Telomeres Lacking TRF2

Jan Karlseder, Dominique Broccoli, Yumin Dai, +2

Science

ChromatinGenome InstabilityDna DamageMedicineGenetics +10

Pim2 is required for maintaining multiple myeloma cell growth through modulating TSC2 phosphorylation

Jing Lü, Tatiana Zavorotinskaya, Yumin Dai, +9

Blood

Antiproliferative and antioxidant properties of anthocyanin-rich extract from açai

Shelly Hogan, Hyun Chung, Lei Zhang, +4

Food Chemistry

MedicinePhytochemicalPharmacologyOxidative StressPolyphenolics +1

Pan-PIM Kinase Inhibition Provides a Novel Therapy for Treating Hematologic Cancers

Pablo D. García, John L. Langowski, Yingyun Wang, +31

Clinical Cancer Research

Smart soft contact lenses for continuous 24-hour monitoring of intraocular pressure in glaucoma care

Jinyuan Zhang, Kyunghun Kim, Ho Joong Kim, +16

Nature Communications

Selective Growth Inhibition of Human Breast Cancer Cells by Graviola Fruit Extract In Vitro and In Vivo Involving Downregulation of EGFR Expression

Yumin Dai, Shelly Hogan, Eva M. Schmelz, +3

Nutrition and Cancer

Substrate‐Assisted, Transition‐Metal‐Free Diboration of Alkynamides with Mixed Diboron: Regio‐ and Stereoselective Access to <i>trans</i>‐1,2‐Vinyldiboronates

Astha Verma, Russell F. Snead, Yumin Dai, +5

Angewandte Chemie International Edition

Materials ScienceSubstrate-assisted DiborationCross-coupling ReactionOrganic Material ChemistryUnsymmetrical Pinacolato-1,8-diaminonaphthalenato Diboron +11

Identification of <i>N</i>-(4-((1<i>R</i>,3<i>S</i>,5<i>S</i>)-3-Amino-5-methylcyclohexyl)pyridin-3-yl)-6-(2,6-difluorophenyl)-5-fluoropicolinamide (PIM447), a Potent and Selective Proviral Insertion Site of Moloney Murine Leukemia (PIM) 1, 2, and 3 Kinase Inhibitor in Clinical Trials for Hematological Malignancies

Matthew T. Burger, Gisele Nishiguchi, Wooseok Han, +29

Journal of Medicinal Chemistry

Hematological MalignancyMoloney Murine LeukemiaMedicinal ChemistryKinase InhibitorMedicine +12

Structure Guided Optimization, in Vitro Activity, and in Vivo Activity of Pan-PIM Kinase Inhibitors

Matthew T. Burger, Wooseok Han, Jiong Lan, +21

ACS Medicinal Chemistry Letters

Drug TargetPan-pim Kinase InhibitorsChemical BiologyTumor BiologyMedicinal Chemistry +17

Antiproliferative Homoisoflavonoids and Bufatrienolides from <i>Urginea depressa</i>

Yumin Dai, Liva Harinantenaina, Peggy J. Brodie, +4

Journal of Natural Products