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HIF-1-mediated expression of pyruvate dehydrogenase kinase: A metabolic switch required for cellular adaptation to hypoxia

Reductive StressSignal TransductionBiochemistryRedox RegulatorMedicinePhysiologyHypoxia (Medicine)Metabolic RemodelingHif-1-mediated ExpressionMetabolismPyruvate Dehydrogenase KinaseMetabolic SwitchRedox BiologyOxidative Stress