Concepedia

Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours

Thomas G. Graeber, Cynthia Osmanian, Tyler Jacks, David E. Housman, Cameron J. Koch, Scott W. Lowe, Amato J. Giaccia

Nature · 1996 · 2.3K citations · 21 references

DOI

Concepts

References

21

Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death

David M. Hockenbery, Gabriel Núñez, Curt Milliman et al. · Nature · 1990 · 3.8K citations

, , +13

Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis.

Marc S. Greenblatt, W P Bennett, Monica Hollstein et al. · PubMed · 1994 · 3.5K citations

, , +16

p53-dependent apoptosis modulates the cytotoxicity of anticancer agents

Scott W. Lowe, H. Earl Ruley, Tyler Jacks et al. · Cell · 1993 · 2.9K citations

, , +14

Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity.

Glen Dranoff, Elizabeth M. Jaffee, A Lazenby et al. · Proceedings of the National Academy of Sciences · 1993 · 2.8K citations

, , +17

Production of high-titer helper-free retroviruses by transient transfection.

Warren S. Pear, Garry P. Nolan, Martin Scott et al. · Proceedings of the National Academy of Sciences · 1993 · 2.3K citations

, , +14