Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death

David M. Hockenbery, Gabriel Núñez, Curt Milliman, +2

Nature

MitophagySignal TransductionMitochondrial FunctionMedicineApoptosis +6

Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis.

Marc S. Greenblatt, W P Bennett, Monica Hollstein, +1

PubMed

Tumor BiologyCancer PathologyMolecular PathogenesisMedicineCancer Cell Biology +7

p53-dependent apoptosis modulates the cytotoxicity of anticancer agents

Scott W. Lowe, H. Earl Ruley, Tyler Jacks, +1

Cell

P53-dependent ApoptosisMedicineApoptosisPharmacologyCell Death +4

Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity.

Glen Dranoff, Elizabeth M. Jaffee, A Lazenby, +7

Proceedings of the National Academy of Sciences

VaccinationIrradiated CellsRadiation OncologyTumor ImmunologyCancer Immunosurveillance +13

Production of high-titer helper-free retroviruses by transient transfection.

Warren S. Pear, Garry P. Nolan, Martin Scott, +1

Proceedings of the National Academy of Sciences

Viral ReplicationXenotransplantationSynthetic VirologyNeurovirologyPathogenesis +11

The Histological Structure of Some Human Lung Cancers and the Possible Implications for Radiotherapy

R. H. Thomlinson, L. H. Gray

British Journal of Cancer

Radiation TherapyHuman Lung CancersMedicineMultiple Pulmonary NodulePossible Implications +10

Mice Lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

Chu‐Xia Deng, Pumin Zhang, J. Wade Harper, +2

Cell

Knockout MouseGenome InstabilityDevelopmental BiologyCell RegulationG1 Checkpoint Control +6

Sunburn and p53 in the onset of skin cancer

Annemarie Ziegler, Alan S. Jonason, David J. Leffellt, +6

Nature

MedicinePhotocarcinogenesisMelanomaDermatologyOncology +3

<i>p53</i> Status and the Efficacy of Cancer Therapy in Vivo

Scott W. Lowe, Stephan Bodis, Andrea I. McClatchey, +5

Science

Cancer TherapyP53 StatusApoptosisPathologyCell Death +15

p53 gene mutations occur in combination with 17p allelic deletions as late events in colorectal tumorigenesis.

Suzanne J. Baker, Antonette C. Preisinger, J. Milburn Jessup, +5

PubMed

GeneticsPathologyTumor BiologyCarcinomaOncology +14