Rob A. Cairns - Concepedia

Author

Rob A. Cairns

Princess Margaret Cancer Centre ORCID

Also Known As

B. Golbourn, Cairns, Rob A, R A Cairns, R. A. Cairns, R. Cairns, Rob A Cairns, Rob A. Cairns, Rob Cairns, Rob A. Cairns

Publications

13.1K

Citations

H-Index

Concepts

All Affiliations

Princess Margaret Cancer Centre University Health Network University of Toronto Ontario Institute for Cancer Research Agios Pharmaceuticals (United States)

About

Rob A. Cairns is an author at Princess Margaret Cancer Centre specializing in medicine, cell biology, and tumor biology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	8	8	3.2K
2	Cell Biology	6	6	2.9K
3	Biochemistry	3	3	173
4	Health Sciences	2	2	324
5	Natural Sciences	1	1	197

Rob A. Cairns

Publications

7.1K

Citations

H-Index

Page 1

	Year	Citations
HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption Ioanna Papandreou, Rob A. Cairns, Lucrezia Fontana, Cell Metabolism Mitochondrial Oxygen ConsumptionRedox RegulatorCell SignalingPhysiologyHypoxia (Medicine)	2006	2.2K
Hexokinase 2 is a key mediator of aerobic glycolysis and promotes tumor growth in human glioblastoma multiforme Amparo Wolf, Sameer Agnihotri, Johann Micallef, The Journal of Experimental Medicine	2011	782
Cancer-associated metabolite 2-hydroxyglutarate accumulates in acute myelogenous leukemia with isocitrate dehydrogenase 1 and 2 mutations Rob A. Cairns, Mark D. Minden, Edward M. Driggers, The Journal of Experimental Medicine	2010	721
IDH2 mutations are frequent in angioimmunoblastic T-cell lymphoma Rob A. Cairns, Javeed Iqbal, François Lemonnier, Blood	2012	491
Recurrent TET2 mutations in peripheral T-cell lymphomas correlate with TFH-like features and adverse clinical parameters François Lemonnier, Lucile Couronné, Marie Parrens, Blood	2012	483
D-2-hydroxyglutarate produced by mutant IDH1 perturbs collagen maturation and basement membrane function Masato Sasaki, Christiane B. Knobbe‐Thomsen, Momoe Itsumi, Genes & Development	2012	296
Acute (cyclic) hypoxia enhances spontaneous metastasis of KHT murine tumors. Rob A. Cairns, Tuula Kalliomäki, Rićhard P. Hill PubMed PathologyCancer BiologyTumor BiologyOxidative StressChronic Hypoxia	2001	293
Acute Hypoxia Enhances Spontaneous Lymph Node Metastasis in an Orthotopic Murine Model of Human Cervical Carcinoma Rob A. Cairns, Rićhard P. Hill Cancer Research	2004	215
Mutant IDH1 Downregulates ATM and Alters DNA Repair and Sensitivity to DNA Damage Independent of TET2 Satoshi Inoue, Wanda Y. Li, Alan Tseng, Cancer Cell Genome InstabilityDna DamageAlters Dna RepairNatural SciencesGenetics	2016	197
Oxygen Consumption Can Regulate the Growth of Tumors, a New Perspective on the Warburg Effect Yijun Chen, Rob A. Cairns, Ioanna Papandreou, PLoS ONE	2009	189

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