Combined Inhibition of DYRK1A, SMAD, and Trithorax Pathways Synergizes to Induce Robust Replication in Adult Human Beta Cells

Positional Cloning of the Gene for Multiple Endocrine Neoplasia-Type 1

Settara C. Chandrasekharappa, Siradanahalli C. Guru, Pachiappan Manickam et al. · Science · 1997 · 2.1K citations

Medicine, Genetics, Molecular Genetics +17

Generation of Functional Human Pancreatic β Cells In Vitro

Felicia W. Pagliuca, Jeffrey R. Millman, Mads Gürtler et al. · Cell · 2014 · 2K citations · Full text

Life Sciences, Cell Biology, Physiology +12

Pancreatic β Cell Dedifferentiation as a Mechanism of Diabetic β Cell Failure

Chutima Talchai, Shouhong Xuan, Hua Lin et al. · Cell · 2012 · 1.4K citations · Full text

Medicine, Cell Biology, Physiology +14

β-Cell Replication Is the Primary Mechanism Subserving the Postnatal Expansion of β-Cell Mass in Humans

Juris J. Meier, Alexandra E. Butler, Yoshifumi Saisho et al. · Diabetes · 2008 · 686 citations · Full text

Life Sciences, Endocrinology, Physiology +17

Genetic Analysis of Italian Patients with Congenital Hyperinsulinism of Infancy

Paola Sogno Valin, Maria Carla Proverbio, Cecilia Diceglie et al. · Hormone Research in Paediatrics · 2013 · 554 citations

Life Sciences, Genetics, Pediatrics +16