Concepedia

Pancreatic β Cell Dedifferentiation as a Mechanism of Diabetic β Cell Failure

Chutima Talchai, Shouhong Xuan, Hua Lin, Lori Sussel, Domenico Accili

Cell · 2012 · 1.4K citations · 53 references

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53

In vivo reprogramming of adult pancreatic exocrine cells to β-cells

Qiao Zhou, Juliana Brown, Andrew Kanarek et al. · Nature · 2008 · 2K citations · Full text

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The natural history of insulin secretory dysfunction and insulin resistance in the pathogenesis of type 2 diabetes mellitus

Christian Weyer, Clifton Bogardus, David M. Mott et al. · Journal of Clinical Investigation · 1999 · 2K citations · Full text

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Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors

Guoqiang Gu, Jolanta Dubauskaite, Douglas A. Melton · Development · 2002 · 1.5K citations

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Conversion of adult pancreatic α-cells to β-cells after extreme β-cell loss

Fabrizio Thorel, Virginie Népote, Isabelle Avril et al. · Nature · 2010 · 1.1K citations · Full text

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FoxOs Are Lineage-Restricted Redundant Tumor Suppressors and Regulate Endothelial Cell Homeostasis

Ji-Hye Paik, Ramya Kollipara, Gerald Chu et al. · Cell · 2007 · 1K citations · Full text

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