Courtney Ackeifi

A Small Molecule Screen in Stem-Cell-Derived Motor Neurons Identifies a Kinase Inhibitor as a Candidate Therapeutic for ALS

Yin Yang, Shailesh Gupta, Kevin J. Kim et al. · Cell stem cell · 2013 · 297 citations · Full text

Neurodegenerative Diseases, Amyotrophic Lateral Sclerosis, Kinase Inhibitor +11

Combined Inhibition of DYRK1A, SMAD, and Trithorax Pathways Synergizes to Induce Robust Replication in Adult Human Beta Cells

Peng Wang, Esra Karaköse, Hongtao Liu et al. · Cell Metabolism · 2018 · 155 citations · Full text

Robust Replication, Signal Transduction, Signaling Pathway +8

GLP-1 receptor agonists synergize with DYRK1A inhibitors to potentiate functional human β cell regeneration

Courtney Ackeifi, Peng Wang, Esra Karaköse et al. · Science Translational Medicine · 2020 · 116 citations · Full text

Insulin Signaling, Cellular Physiology, Molecular Pharmacology +22

Pharmacologic and genetic approaches define human pancreatic β cell mitogenic targets of DYRK1A inhibitors

Courtney Ackeifi, Ethan Swartz, Kunal Kumar et al. · JCI Insight · 2019 · 55 citations · Full text

Small Molecule Inhibitors, Dual Specificity, Molecular Regulation +18

Nuclear Receptor Coactivators Are Coexpressed with Steroid Receptors and Regulated by Estradiol in Mouse Brain

Christina M. Tognoni, Joseph G. Chadwick, Courtney Ackeifi et al. · Neuroendocrinology · 2011 · 33 citations · Full text