Concepedia

Ethan Swartz

ES

6

Publications

472

Citations

6

H-Index

2018

Active since

Affiliations

Icahn School of Medicine at Mount Sinai(Current)

Discovery Institute

Ethan Swartz is an author at Icahn School of Medicine at Mount Sinai specializing in cell signaling, cell biology, and signal transduction.

Top concepts

MedicineCell BiologyCell SignalingSignal TransductionPharmacologySystems BiologyMolecular SignalingMolecular PharmacologyDiabetesCell Cycle

Publications per year

2018–2020

6

Publications

6

Combined Inhibition of DYRK1A, SMAD, and Trithorax Pathways Synergizes to Induce Robust Replication in Adult Human Beta Cells

Peng Wang, Esra Karaköse, Hongtao Liu et al. · Cell Metabolism · 2018 · 155 citations · Full text

Robust Replication, Signal Transduction, Signaling Pathway +8

GLP-1 receptor agonists synergize with DYRK1A inhibitors to potentiate functional human β cell regeneration

Courtney Ackeifi, Peng Wang, Esra Karaköse et al. · Science Translational Medicine · 2020 · 116 citations · Full text

Insulin Signaling, Cellular Physiology, Molecular Pharmacology +22

Development of Kinase-Selective, Harmine-Based DYRK1A Inhibitors that Induce Pancreatic Human β-Cell Proliferation

Kunal Kumar, Peng Wang, Roberto Sánchez et al. · Journal of Medicinal Chemistry · 2018 · 76 citations · Full text

Pharmacologic and genetic approaches define human pancreatic β cell mitogenic targets of DYRK1A inhibitors

Courtney Ackeifi, Ethan Swartz, Kunal Kumar et al. · JCI Insight · 2019 · 55 citations · Full text

Small Molecule Inhibitors, Dual Specificity, Molecular Regulation +18

Synthesis and Biological Validation of a Harmine-Based, Central Nervous System (CNS)-Avoidant, Selective, Human β-Cell Regenerative Dual-Specificity Tyrosine Phosphorylation-Regulated Kinase A (DYRK1A) Inhibitor

Kunal Kumar, Peng Wang, Jessica Wilson et al. · Journal of Medicinal Chemistry · 2020 · 51 citations · Full text

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