Concepedia

β-Cell Replication Is the Primary Mechanism Subserving the Postnatal Expansion of β-Cell Mass in Humans

Juris J. Meier, Alexandra E. Butler, Yoshifumi Saisho, Travis Monchamp, Ryan Galasso, Anil Bhushan, Robert A. Rizza, Peter C. Butler

Diabetes · 2008 · 679 citations · 38 references

DOIFull text

Open access

Abstract

These data imply that regulation of beta-cell replication during infancy plays a major role in beta-cell mass in adult humans.

References

38

β-Cell Deficit and Increased β-Cell Apoptosis in Humans With Type 2 Diabetes

Alexandra E. Butler, Juliette Janson, Susan Bonner‐Weir et al. · Diabetes · 2003 · 4K citations

Replication of Genome-Wide Association Signals in UK Samples Reveals Risk Loci for Type 2 Diabetes

Eleftheria Zeggini, Michael N. Weedon, Cecilia M. Lindgren et al. · Science · 2007 · 2.2K citations · Full text

, , +20

Five-Year Follow-Up After Clinical Islet Transplantation

Edmond A. Ryan, Breay W. Paty, Peter Senior et al. · Diabetes · 2005 · 1.6K citations · Full text

Pathologic Anatomy of the Pancreas in Juvenile Diabetes Mellitus

W Gepts · Diabetes · 1965 · 1.3K citations

, , +14

Insulin resistance during puberty: results from clamp studies in 357 children.

Antoinette Moran, David R. Jacobs, Julia Steinberger et al. · Diabetes · 1999 · 842 citations

, , +18