Karen K. Takane

Hepatocyte Growth Factor Overexpression in the Islet of Transgenic Mice Increases Beta Cell Proliferation, Enhances Islet Mass, and Induces Mild Hypoglycemia

Adolfo Garcı́a-Ocaña, Karen K. Takane, M.A. Syed et al. · Journal of Biological Chemistry · 2000 · 243 citations · Full text

Life Sciences, Endocrinology, Molecular Biology +14

Combined Inhibition of DYRK1A, SMAD, and Trithorax Pathways Synergizes to Induce Robust Replication in Adult Human Beta Cells

Peng Wang, Esra Karaköse, Hongtao Liu et al. · Cell Metabolism · 2018 · 161 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +9

Transgenic Overexpression of Hepatocyte Growth Factor in the β-Cell Markedly Improves Islet Function and Islet Transplant Outcomes in Mice

Adolfo Garcı́a-Ocaña, Rupangi C. Vasavada, Ana Cebrián et al. · Diabetes · 2001 · 158 citations · Full text

Medicine, Endocrinology, Molecular Biology +17

Induction of Human β-Cell Proliferation and Engraftment Using a Single G1/S Regulatory Molecule, cdk6

Nathalie Fiaschi‐Taesch, Fatimah G. Salim, Jeffrey W. Kleinberger et al. · Diabetes · 2010 · 135 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Induction of β-Cell Proliferation and Retinoblastoma Protein Phosphorylation in Rat and Human Islets Using Adenovirus-Mediated Transfer of Cyclin-Dependent Kinase-4 and Cyclin D1

Irene Cózar‐Castellano, Karen K. Takane, Rita Bottino et al. · Diabetes · 2004 · 130 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17