Positional Cloning of the Gene for Multiple Endocrine Neoplasia-Type 1

Settara C. Chandrasekharappa, Siradanahalli C. Guru, Pachiappan Manickam, +20

Science

Menin Interacts with the AP1 Transcription Factor JunD and Represses JunD-Activated Transcription

Sunita Agarwal, Siradanahalli C. Guru, Christina Heppner, +9

Cell

Transcriptional RegulationGeneticsGene RegulationRepresses Jund-activated TranscriptionGene Expression +3

Menin, the product of the <i>MEN1</i> gene, is a nuclear protein

Siradanahalli C. Guru, Paul K. Goldsmith, A. Lee Burns, +4

Proceedings of the National Academy of Sciences

GeneticsMolecular BiologyMolecular GeneticsCell CycleProtein Genetics +16

Somatic mutation of the MEN1 gene in parathyroid tumours

Christina Heppner, Mary Beth Kester, Sunita Agarwal, +18

Nature Genetics

Somatic MutationSomatic VariantGeneticsParathyroid DiseasePathology +3

Somatic mutations of the MEN1 tumor suppressor gene in sporadic gastrinomas and insulinomas.

Zhengping Zhuang, Alexander O. Vortmeyer, Svetlana Pack, +22

PubMed

Tumor BiologyEndocrine OncologySomatic VariantSomatic MutationsMedicine +10

The tumor suppressor protein menin interacts with NF-κB proteins and inhibits NF-κB-mediated transactivation

Christina Heppner, Karl Y Bilimoria, Sunita Agarwal, +8

Oncogene

Tumor BiologyCell RegulationNf-κb ProteinsMedicineImmunology +7

Allelic deletions on chromosome 11q13 in multiple endocrine neoplasia type 1-associated and sporadic gastrinomas and pancreatic endocrine tumors.

Larisa V. Debelenko, Zhengping Zhuang, M R Emmert-Buck, +10

PubMed

Tissue MicrodissectionPathologyChromosome 11Q13Tumor BiologyEndocrine Oncology +14

Human Slug Is a Repressor That Localizes to Sites of Active Transcription

Kirugaval Hemavathy, Siradanahalli C. Guru, John C. Harris, +2

Molecular and Cellular Biology

Molecular RegulationEpigeneticsActive TranscriptionTranscriptional RegulationHuman Slug +14

Allelic deletions on chromosome 11q13 in multiple tumors from individual MEN1 patients.

Irina A. Lubensky, Larisa V. Debelenko, Zhengping Zhuang, +10

PubMed

Tissue MicrodissectionCancer PathologyCytogeneticsGeneticsPathology +16

Common ancestral mutations in theMEN1 gene is likely responsible for the prolactinoma variant of MEN1 (MEN1Burin) in four kindreds from Newfoundland

Shodimu-Emmanuel Olufemi, Jane S. Green, Pachiappan Manickam, +9

Human Mutation