Controlling the False Discovery Rate: A Practical and Powerful Approach to Multiple Testing

Yoav Benjamini, Yosef Hochberg

Journal of the Royal Statistical Society Series B (Statistical Methodology)

EngineeringStatistical FoundationPowerful ApproachDiagnosisData Mining +19

NCBI GEO: archive for functional genomics data sets—update

Tanya Barrett, Stephen E. Wilhite, Pierre Ledoux, +14

Nucleic Acids Research

Functional GenomicsEngineeringBiological DatabaseBioinformatics DatabaseMedicine +13

Statistical significance for genomewide studies

John D. Storey, Robert Tibshirani

Proceedings of the National Academy of Sciences

GeneticsGenomicsHigh Throughput SequencingFalse Positive RateGenome-wide Association Studies +19

Gene expression profiling predicts clinical outcome of breast cancer

Laura van ‘t Veer, Hongyue Dai, Marc J. van de Vijver, +13

Nature

Systems BiologyEngineeringBreast OncologyMedicineCancer Genomics +7

PD-1 Blockade in Tumors with Mismatch-Repair Deficiency

Dung T. Le, Jennifer N. Uram, Hao Wang, +32

New England Journal of Medicine

The Cancer Genome Atlas Pan-Cancer analysis project

John N. Weinstein, Gordon B. Mills, Kenna Shaw, +5

Nature Genetics

A Multigene Assay to Predict Recurrence of Tamoxifen-Treated, Node-Negative Breast Cancer

Soonmyung Paik, Steven Shak, Gong Tang, +12

New England Journal of Medicine

The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups

Nature

Radiation OncologyTranscriptomic ArchitectureEngineeringBreast OncologyTumor Heterogeneity +8

TGFβ attenuates tumour response to PD-L1 blockade by contributing to exclusion of T cells

Sanjeev Mariathasan, Shannon J. Turley, Dorothee Nickles, +39

Nature

Tumor BiologyCancer ImmunosurveillanceTumour ResponsePd-l1 BlockadeT Cells +10

Pan-cancer Immunogenomic Analyses Reveal Genotype-Immunophenotype Relationships and Predictors of Response to Checkpoint Blockade

Pornpimol Charoentong, Francesca Finotello, Mihaela Angelova, +5

Cell Reports

Machine LearningGenomic LandscapesImmunologyPathologyImmunotherapy +14