TIMER2.0 for analysis of tumor-infiltrating immune cells

Taiwen Li, Jingxin Fu, Zexian Zeng, +5

Nucleic Acids Research

Signatures of T cell dysfunction and exclusion predict cancer immunotherapy response

Peng Jiang, Shengqing Gu, Deng Pan, +12

Nature Medicine

Cancer ImmunosurveillanceT Cell DysfunctionT-regulatory CellImmunologyTumor Immunity +8

Large-scale public data reuse to model immunotherapy response and resistance

Jingxin Fu, Karen Li, Wubing Zhang, +4

Genome Medicine

Therapeutically Increasing MHC-I Expression Potentiates Immune Checkpoint Blockade

Shengqing Gu, Wubing Zhang, Xiaoqing Wang, +30

Cancer Discovery

Landscape of B cell immunity and related immune evasion in human cancers

Xihao Hu, Jian Zhang, Jin Wang, +17

Nature Genetics

Cancer ImmunosurveillanceB Cell ImmunityImmunologyTumor ImmunityImmunoediting +5

In vivo CRISPR screens identify the E3 ligase Cop1 as a modulator of macrophage infiltration and cancer immunotherapy target

Xiaoqing Wang, Collin Tokheim, Shengqing Gu, +19

Cell

MedicineImmunologyTumor ImmunityVivo Crispr ScreensGene Editing +7

TISMO: syngeneic mouse tumor database to model tumor immunity and immunotherapy response

Zexian Zeng, Cheryl J. Wong, Lin Yang, +17

Nucleic Acids Research

Preexisting tumor-resident T cells with cytotoxic potential associate with response to neoadjuvant anti–PD-1 in head and neck cancer

Giacomo Oliveira, Ann Marie Egloff, Alexander B. Afeyan, +36

Science Immunology

Inhibition of MAN2A1 Enhances the Immune Response to Anti–PD-L1 in Human Tumors

Sailing Shi, Shengqing Gu, Tong Han, +11

Clinical Cancer Research

Immune receptor repertoires in pediatric and adult acute myeloid leukemia

Jian Zhang, Xihao Hu, Jin Wang, +14

Genome Medicine