Concepedia

T Cell Exclusion

T Cell Exclusion is a tumor-intrinsic resistance mechanism characterized by the physical and functional barriers that prevent cytotoxic T lymphocytes from infiltrating the tumor parenchyma, thereby limiting immune-mediated destruction.

72

Publications

18.3K

Citations

913

Authors

276

Institutions

Publications per year

2017–2026

62

Parents

Publications

72

Signatures of T cell dysfunction and exclusion predict cancer immunotherapy response

Peng Jiang, Shengqing Gu, Deng Pan et al. · Nature Medicine · 2018 · 5.6K citations · Full text

, , +14

TGFβ attenuates tumour response to PD-L1 blockade by contributing to exclusion of T cells

Sanjeev Mariathasan, Shannon J. Turley, Dorothee Nickles et al. · Nature · 2018 · 5.5K citations

, , +16

A Cancer Cell Program Promotes T Cell Exclusion and Resistance to Checkpoint Blockade

Livnat Jerby‐Arnon, Parin Shah, Michael S. Cuoco et al. · Cell · 2018 · 1.4K citations · Full text

, , +12

Genetic Mechanisms of Immune Evasion in Colorectal Cancer

Catherine S. Grasso, Marios Giannakis, Daniel K. Wells et al. · Cancer Discovery · 2018 · 550 citations · Full text

, , +17

Molecular Drivers of the Non–T-cell-Inflamed Tumor Microenvironment in Urothelial Bladder Cancer

Randy F. Sweis, Stefani Spranger, Riyue Bao et al. · Cancer Immunology Research · 2016 · 350 citations · Full text

, , +17

1–5 of 72

Authors

913

  1. RB
    Riyue Bao

    University of Chicago, United States

    4 publications · 449 citations

    4

    h-index

  2. SS
    Stefani Spranger

    University of Chicago, United States

    4 publications · 566 citations

    4

    h-index

  3. RF
    Randy F. Sweis

    University of Chicago, United States

    3 publications · 408 citations

    3

    h-index

  4. JJ
    Jason J. Luke

    University of Chicago, United States

    3 publications · 239 citations

    3

    h-index

  5. SJ
    Shannon J. Turley

    Harvard University, United States

    3 publications · 6K citations

    3

    h-index

1–5 of 913

Institutions

276

  1. University of Chicago

    Chicago, United States

    6 h-index

    29 publications

    4.1K citations

  2. Dana-Farber Cancer Institute

    Boston, United States

    5 h-index

    68 publications

    113.4K citations

  3. Inserm

    Paris, France

    5 h-index

    56 publications

    7K citations

  4. The University of Texas MD Anderson Cancer Center

    Houston, United States

    4 h-index

    13 publications

    4.9K citations

  5. University of Pennsylvania

    Philadelphia, United States

    4 h-index

    14 publications

    3.5K citations

  6. Harvard University

    Cambridge, United States

    4 h-index

    16 publications

    52.9K citations

  7. Johns Hopkins University

    Baltimore, United States

    3 h-index

    7 publications

    615 citations

  8. Center for Cancer Research

    Bethesda, United States

    3 h-index

    6 publications

    4.6K citations

1–8 of 276

Venues

  1. Journal of Clinical Investigation

    JCI · 5 publications · 603 citations

    5

    h-index

  2. Cancer Immunology Research

    5 publications · 540 citations

    5

    h-index

  3. Journal for ImmunoTherapy of Cancer

    JITC · 4 publications · 348 citations

    4

    h-index

  4. Nature Communications

    4 publications · 536 citations

    4

    h-index

  5. Cancer Research

    3 publications · 217 citations

    3

    h-index

1–5