Concepedia

Multi-target-directed ligands for treating Alzheimer's disease: Butyrylcholinesterase inhibitors displaying antioxidant and neuroprotective activities

Damijan Knez, Nicolas Coquelle, Anja Pišlar, Simon Žakelj, Marko Jukič, Matej Sova, Janez Mravljak, Florian Nachon, Xavier Brazzolotto, Janko Kos,

European Journal of Medicinal Chemistry · 2018 · 93 citations · 30 references

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DPPH antioxidant assay revisited

Om P. Sharma, T. K. Bhat · Food Chemistry · 2008 · 1.9K citations

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MDCK (Madin-Darby Canine Kidney) Cells: A Tool for Membrane Permeability Screening

Jennifer D. Irvine, Lori H. Takahashi, Karen Lockhart et al. · Journal of Pharmaceutical Sciences · 1999 · 976 citations

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Selective butyrylcholinesterase inhibition elevates brain acetylcholine, augments learning and lowers Alzheimer β-amyloid peptide in rodent

Nigel H. Greig, Tadanobu Utsuki, Donald K. Ingram et al. · Proceedings of the National Academy of Sciences · 2005 · 723 citations · Full text

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Knowledge-Based, Central Nervous System (CNS) Lead Selection and Lead Optimization for CNS Drug Discovery

Arup K. Ghose, Torsten Herbertz, Robert L. Hudkins et al. · ACS Chemical Neuroscience · 2011 · 437 citations · Full text

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Discovery, Biological Evaluation, and Crystal Structure of a Novel Nanomolar Selective Butyrylcholinesterase Inhibitor

Boris Brus, Urban Košak, Anja Pišlar et al. · Journal of Medicinal Chemistry · 2014 · 279 citations · Full text

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