Xavier Brazzolotto

Genetic ablations of iron regulatory proteins 1 and 2 reveal why iron regulatory protein 2 dominates iron homeostasis

Esther G. Meyron‐Holtz, Manik C. Ghosh, Kazuhiro Iwaï et al. · The EMBO Journal · 2004 · 408 citations · Full text

Life Sciences, Genetics, Molecular Biology +12

Comparison of the Binding of Reversible Inhibitors to Human Butyrylcholinesterase and Acetylcholinesterase: A Crystallographic, Kinetic and Calorimetric Study

Terrone L. Rosenberry, Xavier Brazzolotto, Ian R. Macdonald et al. · Molecules · 2017 · 293 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

Development of an in-vivo active reversible butyrylcholinesterase inhibitor

Urban Košak, Boris Brus, Damijan Knez et al. · Scientific Reports · 2016 · 163 citations · Full text

Medicine, Neuroscience, Pharmacology +17

Biochemical characterization of the HydE and HydG iron‐only hydrogenase maturation enzymes from <i>Thermatoga maritima</i>

Jon K. Rubach, Xavier Brazzolotto, Jacques Gaillard et al. · FEBS Letters · 2005 · 158 citations

Life Sciences, Biochemistry, Microbiology +17

The Magic of Crystal Structure-Based Inhibitor Optimization: Development of a Butyrylcholinesterase Inhibitor with Picomolar Affinity and in Vivo Activity

Urban Košak, Boris Brus, Damijan Knez et al. · Journal of Medicinal Chemistry · 2017 · 156 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17