Florian Nachon

Crystal Structure of Human Butyrylcholinesterase and of Its Complexes with Substrate and Products

Yvain Nicolet, Oksana Lockridge, Patrick Masson et al. · Journal of Biological Chemistry · 2003 · 830 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Crystal structures of human cholinesterases in complex with huprine W and tacrine: elements of specificity for anti-Alzheimer's drugs targeting acetyl- and butyryl-cholinesterase

Florian Nachon, E. Carletti, Cyril Ronco et al. · Biochemical Journal · 2013 · 465 citations

Life Sciences, Medicinal Chemistry, Pharmacology +17

Reactivators of Acetylcholinesterase Inhibited by Organophosphorus Nerve Agents

Guillaume Mercey, Tristan Verdelet, Julien Renou et al. · Accounts of Chemical Research · 2012 · 401 citations

Life Sciences, Pharmacology, Toxicology +17

Comparison of the Binding of Reversible Inhibitors to Human Butyrylcholinesterase and Acetylcholinesterase: A Crystallographic, Kinetic and Calorimetric Study

Terrone L. Rosenberry, Xavier Brazzolotto, Ian R. Macdonald et al. · Molecules · 2017 · 293 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

Development of an in-vivo active reversible butyrylcholinesterase inhibitor

Urban Košak, Boris Brus, Damijan Knez et al. · Scientific Reports · 2016 · 163 citations · Full text

Medicine, Neuroscience, Pharmacology +17