Julien Renou

Reactivators of Acetylcholinesterase Inhibited by Organophosphorus Nerve Agents

Guillaume Mercey, Tristan Verdelet, Julien Renou et al. · Accounts of Chemical Research · 2012 · 393 citations

Design, synthesis and biological evaluation of novel tetrahydroacridine pyridine- aldoxime and -amidoxime hybrids as efficient uncharged reactivators of nerve agent-inhibited human acetylcholinesterase

Maria Kliachyna, Gianluca Santoni, Valentin Nussbaum et al. · European Journal of Medicinal Chemistry · 2014 · 77 citations · Full text

Medicinal Chemistry, -Amidoxime Hybrids, Bioorganic Chemistry +11

Potent 3‐Hydroxy‐2‐Pyridine Aldoxime Reactivators of Organophosphate‐Inhibited Cholinesterases with Predicted Blood–Brain Barrier Penetration

Tamara Zorbaz, Anissa Braïki, Nikola Maraković et al. · Chemistry - A European Journal · 2018 · 64 citations

Crystal Structure, Bioorganic Chemistry, Aldo-keto Reductase +23

Syntheses and in vitro evaluations of uncharged reactivators for human acetylcholinesterase inhibited by organophosphorus nerve agents

Julien Renou, Guillaume Mercey, Tristan Verdelet et al. · Chemico-Biological Interactions · 2012 · 57 citations

Molecular Pharmacology, Biochemistry, Medicine +8

Phenyltetrahydroisoquinoline–Pyridinaldoxime Conjugates as Efficient Uncharged Reactivators for the Dephosphylation of Inhibited Human Acetylcholinesterase

Guillaume Mercey, Julien Renou, Tristan Verdelet et al. · Journal of Medicinal Chemistry · 2012 · 54 citations · Full text

Medicinal Chemistry, New Family, Inhibited Human Acetylcholinesterase +12