Simon Žakelj

Development of an in-vivo active reversible butyrylcholinesterase inhibitor

Urban Košak, Boris Brus, Damijan Knez et al. · Scientific Reports · 2016 · 159 citations · Full text

The Magic of Crystal Structure-Based Inhibitor Optimization: Development of a Butyrylcholinesterase Inhibitor with Picomolar Affinity and in Vivo Activity

Urban Košak, Boris Brus, Damijan Knez et al. · Journal of Medicinal Chemistry · 2017 · 151 citations · Full text

Combinatorial Chemistry, Scopolamine Model, Neurochemical Biomarkers +23

Multi-target-directed ligands for treating Alzheimer's disease: Butyrylcholinesterase inhibitors displaying antioxidant and neuroprotective activities

Damijan Knez, Nicolas Coquelle, Anja Pišlar et al. · European Journal of Medicinal Chemistry · 2018 · 91 citations · Full text

Alzheimer's Disease, Biochemistry, Butyrylcholinesterase Inhibitors +9

Determination of permeability coefficients of ophthalmic drugs through different layers of porcine, rabbit and bovine eyes

Christian Loch, Simon Žakelj, Albin Kristl et al. · European Journal of Pharmaceutical Sciences · 2012 · 86 citations

Animal Physiology, Ophthalmology, Experimental Ophthalmology +13

The effect of lipid composition and liposome size on the release properties of liposomes-in-hydrogel

Julia Hurler, Simon Žakelj, Janez Mravljak et al. · International Journal of Pharmaceutics · 2013 · 75 citations · Full text

Biopolymer Gel, Nanomedicine, Lipid Preparation +7