Concepedia

Aspartate is an endogenous metabolic limitation for tumour growth

Lucas B. Sullivan, Alba Luengo, Laura V. Danai, Lauren N. Bush, Frances F. Diehl, Aaron M. Hosios, Allison N. Lau, Sarah Elmiligy, Scott Malstrom, Caroline A. Lewis,

Nature Cell Biology · 2018 · 357 citations · 29 references

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29

Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells

Cosimo Commisso, Shawn M. Davidson, Rengin G. Soydaner-Azeloglu et al. · Nature · 2013 · 1.7K citations

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An Essential Role of the Mitochondrial Electron Transport Chain in Cell Proliferation Is to Enable Aspartate Synthesis

Kıvanç Birsoy, Walter W. Chen, Elizaveta Freinkman et al. · Cell · 2015 · 1.4K citations · Full text

, , +12

Supporting Aspartate Biosynthesis Is an Essential Function of Respiration in Proliferating Cells

Lucas B. Sullivan, Dan Y. Gui, Aaron M. Hosios et al. · Cell · 2015 · 1.2K citations

, , +15

Metabolic Heterogeneity in Human Lung Tumors

Christopher T. Hensley, Brandon Faubert, Qing Yuan et al. · Cell · 2016 · 1.1K citations · Full text

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Metformin inhibits mitochondrial complex I of cancer cells to reduce tumorigenesis

William W. Wheaton, Samuel E. Weinberg, Robert B. Hamanaka et al. · eLife · 2014 · 1.1K citations · Full text

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