William W. Wheaton

Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity

Frank Weinberg, Robert B. Hamanaka, William W. Wheaton et al. · Proceedings of the National Academy of Sciences · 2010 · 1.7K citations · Full text

Reductive carboxylation supports growth in tumour cells with defective mitochondria

Andrew R. Mullen, William W. Wheaton, Eunsook S. Jin et al. · Nature · 2011 · 1.3K citations · Full text

Biochemistry, Mitochondrial Function, Organelle Dynamic +7

Metformin inhibits mitochondrial complex I of cancer cells to reduce tumorigenesis

William W. Wheaton, Samuel E. Weinberg, Robert B. Hamanaka et al. · eLife · 2014 · 1.1K citations · Full text

Embryonic and tumorigenic pathways converge via Nodal signaling: role in melanoma aggressiveness

Jolanta M. Topczewska, Lynne‐Marie Postovit, Naira V. Margaryan et al. · Nature Medicine · 2006 · 438 citations

Developmental Biology, Cell Regulation, Medicine +8

Human embryonic stem cell microenvironment suppresses the tumorigenic phenotype of aggressive cancer cells

Lynne‐Marie Postovit, Naira V. Margaryan, Elisabeth A. Seftor et al. · Proceedings of the National Academy of Sciences · 2008 · 287 citations · Full text

Adult Stem Cell, Biological Microenvironments, Tumorigenic Phenotype +17