Frank Weinberg

Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity

Frank Weinberg, Robert B. Hamanaka, William W. Wheaton et al. · Proceedings of the National Academy of Sciences · 2010 · 1.7K citations

Life Sciences, Cancer Biology, Oncology +17

Hypoxic activation of AMPK is dependent on mitochondrial ROS but independent of an increase in AMP/ATP ratio

Brooke M. Emerling, Frank Weinberg, Colleen M. Snyder et al. · Free Radical Biology and Medicine · 2009 · 325 citations

Life Sciences, Biochemistry, Cell Biology +16

PTEN regulates p300-dependent hypoxia-inducible factor 1 transcriptional activity through Forkhead transcription factor 3a (FOXO3a)

Brooke M. Emerling, Frank Weinberg, Juinn-Lin Liu et al. · Proceedings of the National Academy of Sciences · 2008 · 217 citations · Full text

Medicine, Cell Biology, Oncology +16

A chemical genomics screen highlights the essential role of mitochondria in HIF-1 regulation

Caroline A. David, Jennifer B. Donnelly, Mike R Michaelides et al. · Proceedings of the National Academy of Sciences · 2008 · 114 citations · Full text

Medicine, Oncology, Pharmacology +17

Generation of Human Fatty Livers Using Custom-Engineered Induced Pluripotent Stem Cells with Modifiable SIRT1 Metabolism

Alexandra Collin de l’Hortet, Kazuki Takeishi, Jorge Guzman‐Lepe et al. · Cell Metabolism · 2019 · 103 citations · Full text

Life Sciences, Biotechnology, Molecular Genetics +11